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Hsp90 inhibition ameliorates CD4(+) T cell‐mediated acute Graft versus Host disease in mice

INTRODUCTION: For many patients with leukemia only allogeneic bone marrow transplantion provides a chance of cure. Co‐transplanted mature donor T cells mediate the desired Graft versus Tumor (GvT) effect required to destroy residual leukemic cells. The donor T cells very often, however, also attack...

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Detalles Bibliográficos
Autores principales: Berges, Carsten, Kerkau, Thomas, Werner, Sandra, Wolf, Nelli, Winter, Nadine, Hünig, Thomas, Einsele, Hermann, Topp, Max S., Beyersdorf, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134726/
https://www.ncbi.nlm.nih.gov/pubmed/27980780
http://dx.doi.org/10.1002/iid3.127