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Distinct immunological activation profiles of dSLIM® and ProMune® depend on their different structural context

INTRODUCTION: DNA‐based TLR9 agonists are potent activators of the immune system. ProMune® and dSLIM® belong to different families of TLR9 agonists and both have been established as cancer immunotherapeutics in clinical proof‐of‐concept studies. Unfortunately, ProMune® failed in pivotal oncological...

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Detalles Bibliográficos
Autores principales:	Kapp, Kerstin, Schneider, Jacqueline, Schneider, Lisa, Gollinge, Nadine, Jänsch, Stefanie, Schroff, Matthias, Wittig, Burghardt, Kleuss, Christiane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134728/ https://www.ncbi.nlm.nih.gov/pubmed/27980779 http://dx.doi.org/10.1002/iid3.126

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