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Modelling GTPase dynamics to understand RhoA-driven cancer cell invasion
Metastasis, initially driven by cells migrating and invading through the local environment, leads to most cancer-associated deaths. Cells can use a variety of modes to move in vitro, all of which depend on Rho GTPases at some level. While traditionally it was thought that Rac1 activity drives protru...
Autores principales: | Hetmanski, Joseph H.R., Schwartz, Jean-Marc, Caswell, Patrick T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134997/ https://www.ncbi.nlm.nih.gov/pubmed/27913679 http://dx.doi.org/10.1042/BST20160184 |
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