TLR3-Induced Maturation of Murine Dendritic Cells Regulates CTL Responses by Modulating PD-L1 Trafficking

Targeting TLR3 through formulations of polyI:C is widely studied as an adjuvant in cancer immunotherapy. The efficacy of such targeting has been shown to increase in combination with anti-PD-L1 treatment. Nevertheless, the mechanistic details of the effect of polyI:C on DC maturation and the impact...

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Detalles Bibliográficos
Autores principales: Varthaman, Aditi, Moreau, Hélène D., Maurin, Mathieu, Benaroch, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135054/
https://www.ncbi.nlm.nih.gov/pubmed/27911948
http://dx.doi.org/10.1371/journal.pone.0167057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135054/
https://www.ncbi.nlm.nih.gov/pubmed/27911948
http://dx.doi.org/10.1371/journal.pone.0167057

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