Sustained-release liquisolid compact tablets containing artemether–lumefantrine as alternate-day regimen for malaria treatment to improve patient compliance

The present study aimed to develop low-dose liquisolid tablets of two antimalarial drugs artemether–lumefantrine (AL) from a nanostructured lipid carrier (NLC) of lumefantrine (LUM) and estimate the potential of AL as an oral delivery system in malariogenic Wistar mice. LUM-NLCs were prepared by hot...

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Detalles Bibliográficos
Autores principales: Nnamani, Petra Obioma, Ugwu, Agatha Adaora, Ibezim, Emmanuel Chinedu, Kenechukwu, Franklin Chimaobi, Akpa, Paul Achile, Ogbonna, John-Dike Nwabueze, Obitte, Nicholas Chinedu, Odo, Amelia Ngozi, Windbergs, Maike, Lehr, Claus-Michael, Attama, Anthony Amaechi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135285/
https://www.ncbi.nlm.nih.gov/pubmed/27932882
http://dx.doi.org/10.2147/IJN.S92755

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