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Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination

Protein Kinase A (PKA) mediates synaptic plasticity and is widely implicated in learning and memory. The hippocampal dentate gyrus (DG) is thought to be responsible for processing and encoding distinct contextual associations in response to highly similar inputs. The mossy fiber (MF) axons of the de...

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Detalles Bibliográficos
Autores principales: Jones, Brian W, Deem, Jennifer, Younts, Thomas J, Weisenhaus, Michael, Sanford, Christina A, Slack, Margaret C, Chin, Jenesa, Nachmanson, Daniela, McKennon, Alex, Castillo, Pablo E, McKnight, G Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135391/
https://www.ncbi.nlm.nih.gov/pubmed/27911261
http://dx.doi.org/10.7554/eLife.20695