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Vogt–Koyanagi–Harada syndrome – current perspectives
Vogt–Koyanagi–Harada syndrome is a cause of noninfectious panuveitis, leading to significant vision loss in many patients. It is an autoimmune disease occurring in genetically susceptible individuals and clinically presents as bilateral panuveitis with serous retinal detachments and hyperemic, swoll...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135404/ https://www.ncbi.nlm.nih.gov/pubmed/27932857 http://dx.doi.org/10.2147/OPTH.S94866 |
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author | Baltmr, Abeir Lightman, Sue Tomkins-Netzer, Oren |
author_facet | Baltmr, Abeir Lightman, Sue Tomkins-Netzer, Oren |
author_sort | Baltmr, Abeir |
collection | PubMed |
description | Vogt–Koyanagi–Harada syndrome is a cause of noninfectious panuveitis, leading to significant vision loss in many patients. It is an autoimmune disease occurring in genetically susceptible individuals and clinically presents as bilateral panuveitis with serous retinal detachments and hyperemic, swollen optic discs, which are associated with neurological and auditory manifestations. Early diagnosis and prompt and adequate treatment with immunosuppressive agents (corticosteroids and other immunosuppressive drugs) may halt disease progression and prevent recurrences and vision loss. This review summarizes the current knowledge on the variable clinical aspects of this disease, highlighting diagnostic and treatment strategies. |
format | Online Article Text |
id | pubmed-5135404 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-51354042016-12-08 Vogt–Koyanagi–Harada syndrome – current perspectives Baltmr, Abeir Lightman, Sue Tomkins-Netzer, Oren Clin Ophthalmol Review Vogt–Koyanagi–Harada syndrome is a cause of noninfectious panuveitis, leading to significant vision loss in many patients. It is an autoimmune disease occurring in genetically susceptible individuals and clinically presents as bilateral panuveitis with serous retinal detachments and hyperemic, swollen optic discs, which are associated with neurological and auditory manifestations. Early diagnosis and prompt and adequate treatment with immunosuppressive agents (corticosteroids and other immunosuppressive drugs) may halt disease progression and prevent recurrences and vision loss. This review summarizes the current knowledge on the variable clinical aspects of this disease, highlighting diagnostic and treatment strategies. Dove Medical Press 2016-11-24 /pmc/articles/PMC5135404/ /pubmed/27932857 http://dx.doi.org/10.2147/OPTH.S94866 Text en © 2016 Baltmr et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Review Baltmr, Abeir Lightman, Sue Tomkins-Netzer, Oren Vogt–Koyanagi–Harada syndrome – current perspectives |
title | Vogt–Koyanagi–Harada syndrome – current perspectives |
title_full | Vogt–Koyanagi–Harada syndrome – current perspectives |
title_fullStr | Vogt–Koyanagi–Harada syndrome – current perspectives |
title_full_unstemmed | Vogt–Koyanagi–Harada syndrome – current perspectives |
title_short | Vogt–Koyanagi–Harada syndrome – current perspectives |
title_sort | vogt–koyanagi–harada syndrome – current perspectives |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135404/ https://www.ncbi.nlm.nih.gov/pubmed/27932857 http://dx.doi.org/10.2147/OPTH.S94866 |
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