Deficiency of ATP6V1H Causes Bone Loss by Inhibiting Bone Resorption and Bone Formation through the TGF-β1 Pathway

Vacuolar-type H (+)-ATPase (V-ATPase) is a highly conserved, ancient enzyme that couples the energy of ATP hydrolysis to proton transport across vesicular and plasma membranes of eukaryotic cells. Previously reported mutations of various V-ATPase subunits are associated with increased bone density....

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Detalles Bibliográficos
Autores principales: Duan, Xiaohong, Liu, Jin, Zheng, Xueni, Wang, Zhe, Zhang, Yanli, Hao, Ying, Yang, Tielin, Deng, Hongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135442/
https://www.ncbi.nlm.nih.gov/pubmed/27924156
http://dx.doi.org/10.7150/thno.17140

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