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Role of endogenous insulin gene enhancer protein ISL-1 in angiogenesis

OBJECTIVE: To elucidate the role of insulin gene enhancer protein ISL-1 (Islet-1) in angiogenesis and regulation of vascular endothelial growth factor (VEGF) expression in vitro and in vivo. METHODS: siRNA targeting Islet-1 was transfected to human umbilical vein endothelial cell lines (HUVECs). The...

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Detalles Bibliográficos
Autores principales: Xiong, Si-qi, Jiang, Hai-bo, Li, Yan-xiu, Li, Hai-bo, Xu, Hui-zhuo, Wu, Zhen-kai, Zheng, Wei, Xia, Xiao-bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135739/
https://www.ncbi.nlm.nih.gov/pubmed/27994436