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Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil

BACKGROUND: Approximately 8–15% epithelial ovarian cancer patients are BRCA1 or BRCA2 germline mutation carriers. Brazilian inhabitants may have peculiar genetic characteristics associated with ethnic diversity, and studies focusing on the entire BRCA1/BRCA2 gene sequencing in Brazilian ovarian canc...

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Detalles Bibliográficos
Autores principales: Maistro, Simone, Teixeira, Natalia, Encinas, Giselly, Katayama, Maria Lucia Hirata, Niewiadonski, Vivian Dionisio Tavares, Cabral, Larissa Garcia, Ribeiro, Roberto Marques, Gaburo Junior, Nelson, de Gouvêa, Ana Carolina Ribeiro Chaves, Carraro, Dirce Maria, Sabino, Ester Cerdeira, Diz, Maria del Pilar Estevez, Chammas, Roger, de Bock, Geertruida Hendrika, Folgueira, Maria Aparecida Azevedo Koike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135756/
https://www.ncbi.nlm.nih.gov/pubmed/27914478
http://dx.doi.org/10.1186/s12885-016-2966-x

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