Cargando…
Ethyl pyruvate is a novel anti-inflammatory agent to treat multiple inflammatory organ injuries
Ethyl pyruvate (EP) is a simple derivative of pyruvic acid, which is an important endogenous metabolite that can scavenge reactive oxygen species (ROS). Treatment with EP is able to ameliorate systemic inflammation and multiple organ dysfunctions in multiple animal models, such as acute pancreatitis...
Autores principales: | Yang, Runkuan, Zhu, Shengtao, Tonnessen, Tor Inge |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135784/ https://www.ncbi.nlm.nih.gov/pubmed/27980458 http://dx.doi.org/10.1186/s12950-016-0144-1 |
Ejemplares similares
-
HMGB1 and Histones Play a Significant Role in Inducing Systemic Inflammation and Multiple Organ Dysfunctions in Severe Acute Pancreatitis
por: Yang, Runkuan, et al.
Publicado: (2017) -
HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver Failure
por: Yang, Runkuan, et al.
Publicado: (2017) -
Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose
por: Yang, Runkuan, et al.
Publicado: (2012) -
HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicity
por: Yang, Runkuan, et al.
Publicado: (2014) -
An Increased Lactate-to-pyruvate Ratio Is Not a Stand-alone Marker of Ischemia
por: Haugaa, Håkon, et al.
Publicado: (2020)