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Predicting the recurrence of noncoding regulatory mutations in cancer

BACKGROUND: One of the greatest challenges in cancer genomics is to distinguish driver mutations from passenger mutations. Whereas recurrence is a hallmark of driver mutations, it is difficult to observe recurring noncoding mutations owing to a limited amount of whole-genome sequenced samples. Hence...

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Detalles Bibliográficos
Autores principales: Yang, Woojin, Bang, Hyoeun, Jang, Kiwon, Sung, Min Kyung, Choi, Jung Kyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135808/
https://www.ncbi.nlm.nih.gov/pubmed/27912731
http://dx.doi.org/10.1186/s12859-016-1385-y

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