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Fetal malformation in maternal toxoplasma and rubella co-infection in Cameroon: a case report

BACKGROUND: There has been a recent increase in the number of newborns with brain malformations due to congenital infections, but the impact of these diseases remains largely under ascertained in middle-income and low-income countries. This case report presents a fetal anencephaly following maternal...

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Autores principales: Njoh, Andreas Ateke, Njoh, Sarah Namondo, Abizou, Messang Blandine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135823/
https://www.ncbi.nlm.nih.gov/pubmed/27912790
http://dx.doi.org/10.1186/s13256-016-1133-y
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author Njoh, Andreas Ateke
Njoh, Sarah Namondo
Abizou, Messang Blandine
author_facet Njoh, Andreas Ateke
Njoh, Sarah Namondo
Abizou, Messang Blandine
author_sort Njoh, Andreas Ateke
collection PubMed
description BACKGROUND: There has been a recent increase in the number of newborns with brain malformations due to congenital infections, but the impact of these diseases remains largely under ascertained in middle-income and low-income countries. This case report presents a fetal anencephaly following maternal toxoplasma and rubella co-infection in a resource-limited setting and the challenges faced by the patient and the health care provider in the management of the condition. CASE PRESENTATION: A 25-year-old black Cameroonian woman of Bakossi origin, gravida(3) para(1)010, presented with a positive rubella and toxoplasma immunoglobulin G serologic test at 21 weeks of pregnancy; she could not benefit from a fetal morphologic ultrasound partly because there was none at the site of her antenatal clinic and because there were accessibility constraints getting to the nearest referral hospital approximately 100 km away. She returned to the hospital in labor pains 14 weeks later and, upon examination, she was observed to be at almost full cervical dilatation and had a stillbirth a few minutes later; a baby boy weighing 1600 g with anencephaly. The devastated parents of the baby were counseled and given psychological support. She was discharged from hospital 3 days later and now benefits from continual follow up as out-patient. She was advised to consult a gynecologist-obstetrician before her next pregnancy. CONCLUSION: Much attention still has to be paid to ameliorate the health care in resource-limited settings where pregnant women generally obtain less than adequate care. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13256-016-1133-y) contains supplementary material, which is available to authorized users.
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spelling pubmed-51358232016-12-15 Fetal malformation in maternal toxoplasma and rubella co-infection in Cameroon: a case report Njoh, Andreas Ateke Njoh, Sarah Namondo Abizou, Messang Blandine J Med Case Rep Case Report BACKGROUND: There has been a recent increase in the number of newborns with brain malformations due to congenital infections, but the impact of these diseases remains largely under ascertained in middle-income and low-income countries. This case report presents a fetal anencephaly following maternal toxoplasma and rubella co-infection in a resource-limited setting and the challenges faced by the patient and the health care provider in the management of the condition. CASE PRESENTATION: A 25-year-old black Cameroonian woman of Bakossi origin, gravida(3) para(1)010, presented with a positive rubella and toxoplasma immunoglobulin G serologic test at 21 weeks of pregnancy; she could not benefit from a fetal morphologic ultrasound partly because there was none at the site of her antenatal clinic and because there were accessibility constraints getting to the nearest referral hospital approximately 100 km away. She returned to the hospital in labor pains 14 weeks later and, upon examination, she was observed to be at almost full cervical dilatation and had a stillbirth a few minutes later; a baby boy weighing 1600 g with anencephaly. The devastated parents of the baby were counseled and given psychological support. She was discharged from hospital 3 days later and now benefits from continual follow up as out-patient. She was advised to consult a gynecologist-obstetrician before her next pregnancy. CONCLUSION: Much attention still has to be paid to ameliorate the health care in resource-limited settings where pregnant women generally obtain less than adequate care. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13256-016-1133-y) contains supplementary material, which is available to authorized users. BioMed Central 2016-12-03 /pmc/articles/PMC5135823/ /pubmed/27912790 http://dx.doi.org/10.1186/s13256-016-1133-y Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Njoh, Andreas Ateke
Njoh, Sarah Namondo
Abizou, Messang Blandine
Fetal malformation in maternal toxoplasma and rubella co-infection in Cameroon: a case report
title Fetal malformation in maternal toxoplasma and rubella co-infection in Cameroon: a case report
title_full Fetal malformation in maternal toxoplasma and rubella co-infection in Cameroon: a case report
title_fullStr Fetal malformation in maternal toxoplasma and rubella co-infection in Cameroon: a case report
title_full_unstemmed Fetal malformation in maternal toxoplasma and rubella co-infection in Cameroon: a case report
title_short Fetal malformation in maternal toxoplasma and rubella co-infection in Cameroon: a case report
title_sort fetal malformation in maternal toxoplasma and rubella co-infection in cameroon: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135823/
https://www.ncbi.nlm.nih.gov/pubmed/27912790
http://dx.doi.org/10.1186/s13256-016-1133-y
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