A pathway-centric approach to rare variant association analysis

Current endeavours in rare variant analysis are typically underpowered when investigating association signals from individual genes. We undertook an approach to rare variant analysis which utilises biological pathway information to analyse functionally relevant genes together. Conventional filtering...

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Detalles Bibliográficos
Autores principales: Richardson, Tom G, Timpson, Nicholas J, Campbell, Colin, Gaunt, Tom R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136291/
https://www.ncbi.nlm.nih.gov/pubmed/27577545
http://dx.doi.org/10.1038/ejhg.2016.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136291/
https://www.ncbi.nlm.nih.gov/pubmed/27577545
http://dx.doi.org/10.1038/ejhg.2016.113

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