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Activation of NMDA receptors and the mechanism of inhibition by ifenprodil

The physiology of N-Methyl-D-aspartate (NMDA) receptors in mammals is fundamental to brain development and function. NMDA receptors are ionotropic glutamate receptors that function as heterotetramers composed mainly of GluN1 and GluN2 subunits. Activation of NMDA receptors requires binding of neurot...

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Detalles Bibliográficos
Autores principales:	Tajima, Nami, Karakas, Erkan, Grant, Timothy, Simorowski, Noriko, Diaz-Avalos, Ruben, Grigorieff, Nikolaus, Furukawa, Hiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136294/ https://www.ncbi.nlm.nih.gov/pubmed/27135925 http://dx.doi.org/10.1038/nature17679

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