Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum

ABSTRACT: Two rare lyconadin-type Lycopodium alkaloids, lyconadins G (1) and H (2), together with four known ones (3–6), were isolated from Lycopodium complanatum. The structures were determined on the basis of their spectroscopic analyses, and the absolute configuration of 1 was established by an X...

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Autores principales: Cheng, Jin-Tang, Zhang, Zhi-Jun, Li, Xiao-Nian, Peng, Li-Yan, Luo, Huai-Rong, Wu, Xing-De, Zhao, Qin-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136372/
https://www.ncbi.nlm.nih.gov/pubmed/27783309
http://dx.doi.org/10.1007/s13659-016-0111-9
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author Cheng, Jin-Tang
Zhang, Zhi-Jun
Li, Xiao-Nian
Peng, Li-Yan
Luo, Huai-Rong
Wu, Xing-De
Zhao, Qin-Shi
author_facet Cheng, Jin-Tang
Zhang, Zhi-Jun
Li, Xiao-Nian
Peng, Li-Yan
Luo, Huai-Rong
Wu, Xing-De
Zhao, Qin-Shi
author_sort Cheng, Jin-Tang
collection PubMed
description ABSTRACT: Two rare lyconadin-type Lycopodium alkaloids, lyconadins G (1) and H (2), together with four known ones (3–6), were isolated from Lycopodium complanatum. The structures were determined on the basis of their spectroscopic analyses, and the absolute configuration of 1 was established by an X-ray crystallographic analysis. It is the first time to establish the absolute configuration of lyconadin-type Lycopodium alkaloid by an X-ray diffraction experiment. In addition, these findings may provide more information for the biosynthesis of lyconadins. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-016-0111-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-51363722016-12-19 Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum Cheng, Jin-Tang Zhang, Zhi-Jun Li, Xiao-Nian Peng, Li-Yan Luo, Huai-Rong Wu, Xing-De Zhao, Qin-Shi Nat Prod Bioprospect Original Article ABSTRACT: Two rare lyconadin-type Lycopodium alkaloids, lyconadins G (1) and H (2), together with four known ones (3–6), were isolated from Lycopodium complanatum. The structures were determined on the basis of their spectroscopic analyses, and the absolute configuration of 1 was established by an X-ray crystallographic analysis. It is the first time to establish the absolute configuration of lyconadin-type Lycopodium alkaloid by an X-ray diffraction experiment. In addition, these findings may provide more information for the biosynthesis of lyconadins. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-016-0111-9) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2016-10-25 /pmc/articles/PMC5136372/ /pubmed/27783309 http://dx.doi.org/10.1007/s13659-016-0111-9 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Cheng, Jin-Tang
Zhang, Zhi-Jun
Li, Xiao-Nian
Peng, Li-Yan
Luo, Huai-Rong
Wu, Xing-De
Zhao, Qin-Shi
Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum
title Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum
title_full Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum
title_fullStr Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum
title_full_unstemmed Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum
title_short Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum
title_sort lyconadins g and h, two rare lyconadin-type lycopodium alkaloids from lycopodium complanatum
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136372/
https://www.ncbi.nlm.nih.gov/pubmed/27783309
http://dx.doi.org/10.1007/s13659-016-0111-9
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