Indole Glycosides from Aqueous Fraction of Strychnos nitida

Three new indole glycosides 22-deoxystrictosamide (1), 22-deoxystrictosamide N (b)-oxide (2) and vincosamide 2′-O-β-D-xylopyranoside-11-O-β-D-glucopyranoside (3), together with four known analogues were isolated from aqueous fraction of Strychnos nitida. Their structures were elucidated on the basis...

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Detalles Bibliográficos
Autores principales: Wang, Bei, Dai, Zhi, Liu, Lu, Wei, Xin, Zhu, Pei-Feng, Yu, Hao-Fei, Liu, Ya-Ping, Luo, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136373/
https://www.ncbi.nlm.nih.gov/pubmed/27830475
http://dx.doi.org/10.1007/s13659-016-0112-8
Descripción
Sumario:Three new indole glycosides 22-deoxystrictosamide (1), 22-deoxystrictosamide N (b)-oxide (2) and vincosamide 2′-O-β-D-xylopyranoside-11-O-β-D-glucopyranoside (3), together with four known analogues were isolated from aqueous fraction of Strychnos nitida. Their structures were elucidated on the basis of extensive analysis of spectroscopic data. All the alkaloids were tested for their cytotoxic activity, but they did not show any exciting result. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-016-0112-8) contains supplementary material, which is available to authorized users.

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