Autophagy requires poly(adp-ribosyl)ation-dependent AMPK nuclear export

AMPK is a central energy sensor linking extracellular milieu fluctuations with the autophagic machinery. In the current study we uncover that Poly(ADP-ribosyl)ation (PARylation), a post-translational modification (PTM) of proteins, accounts for the spatial and temporal regulation of autophagy by mod...

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Detalles Bibliográficos
Autores principales: Rodríguez-Vargas, José M, Rodríguez, María I, Majuelos-Melguizo, Jara, García-Diaz, Ángel, González-Flores, Ariannys, López-Rivas, Abelardo, Virág, László, Illuzzi, Giuditta, Schreiber, Valerie, Dantzer, Françoise, Oliver, F Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136490/
https://www.ncbi.nlm.nih.gov/pubmed/27689873
http://dx.doi.org/10.1038/cdd.2016.80

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