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Structure and activation of the TSH receptor transmembrane domain

PURPOSE: The thyroid-stimulating hormone receptor (TSHR) is the target autoantigen for TSHR-stimulating autoantibodies in Graves’ disease. The TSHR is composed of: a leucine-rich repeat domain (LRD), a hinge region or cleavage domain (CD) and a transmembrane domain (TMD). The binding arrangements be...

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Detalles Bibliográficos
Autores principales:	Núñez Miguel, Ricardo, Sanders, Jane, Furmaniak, Jadwiga, Smith, Bernard Rees
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136658/ https://www.ncbi.nlm.nih.gov/pubmed/27921237 http://dx.doi.org/10.1007/s13317-016-0090-1

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