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Host cell mTORC1 is required for HCV RNA replication

OBJECTIVE: Chronically HCV-infected orthotopic liver transplantation (OLT) recipients appear to have improved outcomes when their immunosuppressive regimen includes a mammalian target of rapamycin (mTOR) inhibitor. The mechanism underlying this observation is unknown. DESIGN: We used virological ass...

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Detalles Bibliográficos
Autores principales:	Stöhr, Stefanie, Costa, Rui, Sandmann, Lisa, Westhaus, Sandra, Pfaender, Stephanie, Anggakusuma, Dazert, Eva, Meuleman, Philip, Vondran, Florian W R, Manns, Michael P, Steinmann, Eike, von Hahn, Thomas, Ciesek, Sandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2016
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136730/ https://www.ncbi.nlm.nih.gov/pubmed/26276683 http://dx.doi.org/10.1136/gutjnl-2014-308971

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