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KIR Genes and Their Ligands Predict the Response to Anti-EGFR Monoclonal Antibodies in Solid Tumors

Killer-cell immunoglobulin-like receptors (KIRs) regulate the killing function of natural killer cells, which play an important role in the antibody-dependent cell-mediated cytotoxicity response exerted by therapeutic monoclonal antibodies (mAbs). However, it is unknown whether the extensive genetic...

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Detalles Bibliográficos
Autores principales:	Morales-Estevez, Cristina, De la Haba-Rodriguez, Juan, Manzanares-Martin, Barbara, Porras-Quintela, Ignacio, Rodriguez-Ariza, Antonio, Moreno-Vega, Alberto, Ortiz-Morales, Maria J., Gomez-España, Maria A., Cano-Osuna, Maria T., Lopez-Gonzalez, Javier, Chia-Delgado, Beatriz, Gonzalez-Fernandez, Rafael, Aranda-Aguilar, Enrique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136734/ https://www.ncbi.nlm.nih.gov/pubmed/27994592 http://dx.doi.org/10.3389/fimmu.2016.00561

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