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Improved Antitumor Activity of a Therapeutic Melanoma Vaccine through the Use of the Dual COX-2/5-LO Inhibitor Licofelone

Immune-suppressive cell populations impair antitumor immunity and can contribute to the failure of immune therapeutic approaches. We hypothesized that the non-steroidal anti-inflammatory drug licofelone, a dual cyclooxygenase-2/5-LO inhibitor, would improve therapeutic melanoma vaccination by reduci...

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Detalles Bibliográficos
Autores principales:	Neumann, Silke, Shirley, Simon A., Kemp, Roslyn A., Hook, Sarah M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137024/ https://www.ncbi.nlm.nih.gov/pubmed/27994586 http://dx.doi.org/10.3389/fimmu.2016.00537

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