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DNA intercalation optimized by two-step molecular lock mechanism

The diverse properties of DNA intercalators, varying in affinity and kinetics over several orders of magnitude, provide a wide range of applications for DNA-ligand assemblies. Unconventional intercalation mechanisms may exhibit high affinity and slow kinetics, properties desired for potential therap...

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Detalles Bibliográficos
Autores principales: Almaqwashi, Ali A., Andersson, Johanna, Lincoln, Per, Rouzina, Ioulia, Westerlund, Fredrik, Williams, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137138/
https://www.ncbi.nlm.nih.gov/pubmed/27917863
http://dx.doi.org/10.1038/srep37993