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Ubiquitin Ligase NEDD4 Regulates PPARγ Stability and Adipocyte Differentiation in 3T3-L1 Cells
Peroxisome proliferator–activated receptor-γ (PPARγ) is a ligand-activated nuclear receptor which controls lipid and glucose metabolism. It is also the master regulator of adipogenesis. In adipocytes, ligand-dependent PPARγ activation is associated with proteasomal degradation; therefore, regulation...
Autores principales: | Li, Jing Jing, Wang, Ruishan, Lama, Rati, Wang, Xinjiang, Floyd, Z. Elizabeth, Park, Edwards A., Liao, Francesca-Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137149/ https://www.ncbi.nlm.nih.gov/pubmed/27917940 http://dx.doi.org/10.1038/srep38550 |
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