Distinct epigenomes in CD4(+) T cells of newborns, middle-ages and centenarians

Age-related variations in genes and microRNAs expression and DNA methylation have been reported respectively; however, their interactions during aging are unclear. We therefore investigated alterations in the transcriptomes, miRNAomes and DNA methylomes in the same CD4(+)T cells from newborn (NB), m...

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Detalles Bibliográficos
Autores principales: Zhao, Ming, Qin, Jian, Yin, Hanqi, Tan, Yixin, Liao, Wei, Liu, Qian, Luo, Shuangyan, He, Min, Liang, Gongping, Shi, Yajing, Zhang, Qing, Cai, Wenjun, Yin, Guangliang, Zhou, Yin, Wang, Jing, Li, Mengying, Huang, Yi, Liu, Aiyun, Wu, Haijing, Zhang, Zhiyong, Lu, Qianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137168/
https://www.ncbi.nlm.nih.gov/pubmed/27917918
http://dx.doi.org/10.1038/srep38411

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