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LARGE2-dependent glycosylation confers laminin-binding ability on proteoglycans

Both LARGE1 (formerly LARGE) and its paralog LARGE2 are bifunctional glycosyltransferases with xylosy- and glucuronyltransferase activities, and are capable of synthesizing polymers composed of a repeating disaccharide [-3Xylα1,3GlcAβ1-]. Post-translational modification of the O-mannosyl glycan of α...

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Detalles Bibliográficos
Autores principales:	Inamori, Kei-ichiro, Beedle, Aaron M, de Bernabé, Daniel Beltrán-Valero, Wright, Michael E, Campbell, Kevin P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Original articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137251/ https://www.ncbi.nlm.nih.gov/pubmed/27496765 http://dx.doi.org/10.1093/glycob/cww075

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