Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy

Genome-wide mechanisms that coordinate expression of subsets of functionally related genes are largely unknown. Recent studies show that receptor tyrosine kinases and components of signal transduction cascades including the extracellular signal-regulated protein kinase (ERK), once thought to act pre...

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Detalles Bibliográficos
Autores principales: Mikula, M., Skrzypczak, M., Goryca, K., Paczkowska, K., Ledwon, J.K., Statkiewicz, M., Kulecka, M., Grzelak, M., Dabrowska, M., Kuklinska, U., Karczmarski, J., Rumienczyk, I., Jastrzebski, K., Miaczynska, M., Ginalski, K., Bomsztyk, K., Ostrowski, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137434/
https://www.ncbi.nlm.nih.gov/pubmed/27587583
http://dx.doi.org/10.1093/nar/gkw763

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