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Single-molecule FRET reveals the pre-initiation and initiation conformations of influenza virus promoter RNA

Influenza viruses have a segmented viral RNA (vRNA) genome, which is replicated by the viral RNA-dependent RNA polymerase (RNAP). Replication initiates on the vRNA 3′ terminus, producing a complementary RNA (cRNA) intermediate, which serves as a template for the synthesis of new vRNA. RNAP structure...

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Detalles Bibliográficos
Autores principales: Robb, Nicole C., te Velthuis, Aartjan J. W., Wieneke, Ralph, Tampé, Robert, Cordes, Thorben, Fodor, Ervin, Kapanidis, Achillefs N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137447/
https://www.ncbi.nlm.nih.gov/pubmed/27694620
http://dx.doi.org/10.1093/nar/gkw884

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