Cargando…

Importance of measuring testosterone in enzyme-inhibited plasma for oral testosterone undecanoate androgen replacement therapy clinical trials

AIM: Testosterone undecanoate (TU) is metabolized by nonspecific esterases in blood to testosterone (T). Typical clinical practice has been to analyze testosterone in human serum. The degradation of TU to testosterone was evaluated in conditions typically used in clinical studies. METHODS & RESU...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lachance, Sylvain, Dhingra, Om, Bernstein, James, Gagnon, Stéphanie, Savard, Caroline, Pelletier, Nathalie, Boudreau, Nadine, Lévesque, Ann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Science Ltd 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137954/ https://www.ncbi.nlm.nih.gov/pubmed/28031910 http://dx.doi.org/10.4155/fso.15.55

Ejemplares similares

Effects of the oral testosterone undecanoate Kyzatrex™ on ambulatory blood pressure in hypogonadal men
por: White, William B., et al.
Publicado: (2021)

Safety Aspects and Rational Use of Testosterone Undecanoate in the Treatment of Testosterone Deficiency: Clinical Insights
por: Campbell, Katherine, et al.
Publicado: (2023)

Oral testosterone undecanoate is an effective treatment for micropenis therapy
por: Saenger, Paul, et al.
Publicado: (2021)

A New Oral Testosterone Undecanoate Formulation Restores Testosterone to Normal Concentrations in Hypogonadal Men
por: Swerdloff, Ronald S, et al.
Publicado: (2020)

Comparative application of testosterone undecanoate and/or testosterone propionate in induction of benign prostatic hyperplasia in Wistar rats
por: An, Jinho, et al.
Publicado: (2022)

Optimal injection interval for testosterone undecanoate treatment of hypogonadal and transgender men
por: Shankara Narayana, Nandini, et al.
Publicado: (2021)

Strawberry Decreases Intraluminal and Intestinal Wall Hydrolysis of Testosterone Undecanoate
por: Zgair, Atheer, et al.
Publicado: (2021)

Corrigendum for: “A New Oral Testosterone Undecanoate Formulation Restores Testosterone to Normal Concentrations in Hypogonadal Men”
Publicado: (2020)

Anaphylaxis Triggered by Benzyl Benzoate in a Preparation of Depot Testosterone Undecanoate
por: Ong, Gregory S. Y., et al.
Publicado: (2012)

Recovery of Male Reproductive Endocrine Function Following Prolonged Injectable Testosterone Undecanoate Treatment
por: Shankara-Narayana, Nandini, et al.
Publicado: (2021)

Exploring the efficacy of testosterone undecanoate in male children with 5α‐reductase deficiency
por: Liu, Ying, et al.
Publicado: (2021)

Metabolic phenotype of male obesity-related secondary hypogonadism pre-replacement and post-replacement therapy with intra-muscular testosterone undecanoate therapy
por: Dimitriadis, Georgios K., et al.
Publicado: (2018)

Effectiveness of a low dose testosterone undecanoate to improve sexual function in postmenopausal women
por: Tungmunsakulchai, Reuthairat, et al.
Publicado: (2015)

SUN-234 Effect of Testosterone Undecanoate on Metabolic Syndrome Parameters in a Cohort of Hypogonadism
por: Yadav, Subhash Chandra, et al.
Publicado: (2019)

A new oral testosterone undecanoate therapy comes of age for the treatment of hypogonadal men
por: Swerdloff, Ronald S., et al.
Publicado: (2020)

Spectrophotometric and chromatographic strategies for exploring of the nanostructure pharmaceutical formulations which contains testosterone undecanoate
por: Butnariu, Monica, et al.
Publicado: (2020)

Effects of Low-Dose Testosterone Undecanoate Treatment on Bone Mineral Density and Bone Turnover Markers in Elderly Male Osteoporosis with Low Serum Testosterone
por: Wang, Yan-Jiao, et al.
Publicado: (2013)

Alternatives to testosterone replacement: testosterone restoration
por: McCullough, Andrew
Publicado: (2015)

Suppression of spermatogenesis by testosterone undecanoate-loaded injectable in situ-forming implants in adult male rats
por: Zhang, Xiao-Wei, et al.
Publicado: (2016)

Occurrence of Pulmonary Oil Microembolism After Testosterone Undecanoate Injection: A Postmarketing Safety Analysis
por: Pastuszak, Alexander W., et al.
Publicado: (2020)

Pharmacological treatment for pubertal progression in boys with delayed or slow progression of puberty: A small-scale randomized study with testosterone enanthate and testosterone undecanoate treatment
por: Österbrand, Martin, et al.
Publicado: (2023)

Effects of Five-Year Treatment with Testosterone Undecanoate on Metabolic and Hormonal Parameters in Ageing Men with Metabolic Syndrome
por: Francomano, Davide, et al.
Publicado: (2014)

Corrigendum to a new oral testosterone undecanoate (TU) therapy comes of age for the treatment of hypogonadal men
Publicado: (2021)

Safety Analysis of an Oral Testosterone Undecanoate (TU) Formulation Following 2 Years of Administration in Hypogonadal Men
por: Swerdloff, Ronald S, et al.
Publicado: (2021)

Population Pharmacokinetic Modeling and Simulations to Evaluate a Potential Dose Regimen of Testosterone Undecanoate in Hypogonadal Males
por: Pastuszak, Alexander W., et al.
Publicado: (2021)

SUN-227 Monitoring Testosterone (T) Levels in Men Receiving Oral Testosterone Undecanoate (TU): Challenges Due to Post-Collection Conversion of TU-to-T and a Path Forward
por: Swerdloff, Ronald, et al.
Publicado: (2019)

Controversies in testosterone replacement therapy: testosterone and cardiovascular disease
por: Hwang, Kathleen, et al.
Publicado: (2015)

Is Oral Testosterone the New Frontier of Testosterone Replacement Therapy?
por: Ahmad, Syed W, et al.
Publicado: (2022)

Book Review: Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies
por: Moon, Du Geon
Publicado: (2015)

UGT2B17 Genotype and the Pharmacokinetic Serum Profile of Testosterone during Substitution Therapy with Testosterone Undecanoate. A Retrospective Experience from 207 Men with Hypogonadism
por: Bang, Anne Kirstine, et al.
Publicado: (2013)

Testosterone replacement therapy
por: Shoskes, Daniel A., et al.
Publicado: (2016)

Testosterone Replacement Therapy
por: Hellstrom, Wayne J.G.
Publicado: (2004)

PMON267 Comparison Between Single Time Point Testing and 24-Hour Average Concentration of Total Testosterone in Hypogonadal Men Treated with an Oral Testosterone Undecanoate Softgel (JATENZO®)
por: Swerdloff, Ronald, et al.
Publicado: (2022)

Serum Testosterone Level, Testosterone Replacement Treatment, and Prostate Cancer
por: Atan, Ali, et al.
Publicado: (2013)

Recovery of spermatogenesis following testosterone replacement therapy or anabolic-androgenic steroid use
por: McBride, J Abram, et al.
Publicado: (2016)

SAT-038 Ambulatory Blood Pressure Increases in Hypogonadal Men Who Develop Increases in Hematocrit on Oral Testosterone Undecanoate
por: Dobs, Adrian Sandra, et al.
Publicado: (2020)

Development and Comparison of Intramuscularly Injected Long-acting Testosterone Undecanoate Nano-/Microcrystal Suspensions with Three Different Particle Size
por: Jia, Lihua, et al.
Publicado: (2021)

Altered cardiac repolarization associated with cellular electrophysiological remodeling following chronic testosterone undecanoate administration in a canine model
por: Topal, L, et al.
Publicado: (2023)

Testosterone replacement in male hypogonadism
por: Kalra, Sanjay, et al.
Publicado: (2010)

Testosterone replacement and prostate cancer
por: Ramasamy, Ranjith, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_t3ee9pasgpbkhtur0mrt76mtdj