Hyperglycemia during the immediate period following liver transplantation

AIM: High blood glucose levels in the hospital are common among transplant recipients. METHODS: Retrospective analysis, stratified by diagnosis of pretransplant diabetes mellitus (DM). RESULTS: Of 346 patients, 96 had pretransplant DM (insulin, n = 60; no insulin, n = 36) and 250 did not. Patients w...

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Detalles Bibliográficos
Autores principales: Werner, K Tuesday, Mackey, Patricia A, Castro, Janna C, Carey, Elizabeth J, Chakkera, Harini A, Cook, Curtiss B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138006/
https://www.ncbi.nlm.nih.gov/pubmed/28031946
http://dx.doi.org/10.4155/fsoa-2015-0010
Descripción
Sumario:AIM: High blood glucose levels in the hospital are common among transplant recipients. METHODS: Retrospective analysis, stratified by diagnosis of pretransplant diabetes mellitus (DM). RESULTS: Of 346 patients, 96 had pretransplant DM (insulin, n = 60; no insulin, n = 36) and 250 did not. Patients with pretransplant DM had higher inpatient mean glucose levels and more hyperglycemia and hypoglycemia (all p < 0.01). For patients without pretransplant DM, the need for insulin at discharge increased 23% for every 5-year age increase (odds ratio: 1.23; 95% CI: 1.06–1.44; p = 0.007) and 51% for every five units of glucose measurements >180 mg/dl (OR: 1.51; 95% CI: 1.23–1.95; p < 0.01). CONCLUSION: Inpatient hyperglycemia was common in liver transplant recipients. Hospital practitioners must anticipate the need to teach self-management skills to liver transplant recipients.

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