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Multiple nanoemulsion system for an oral combinational delivery of oxaliplatin and 5-fluorouracil: preparation and in vivo evaluation
Oxaliplatin (OXA) is a third-generation cisplatin analog that has been approved as first-line chemotherapy in combination with 5-fluorouracil (5-FU) for the treatment of resectable and advanced colorectal cancer. However, the therapeutic efficacy of oral OXA and 5-FU is limited by their low bioavail...
Autores principales: | Pangeni, Rudra, Choi, Sang Won, Jeon, Ok-Cheol, Byun, Youngro, Park, Jin Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138023/ https://www.ncbi.nlm.nih.gov/pubmed/27942212 http://dx.doi.org/10.2147/IJN.S121114 |
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