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Halogenated indoles eradicate bacterial persister cells and biofilms

The emergence of antibiotic resistance has necessitated new therapeutic approaches to combat recalcitrant bacterial infections. Persister cells, often found in biofilms, are metabolically dormant, and thus, are highly tolerant to all traditional antibiotics and represent a major drug resistance mech...

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Detalles Bibliográficos
Autores principales: Lee, Jin-Hyung, Kim, Yong-Guy, Gwon, Giyeon, Wood, Thomas K., Lee, Jintae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138170/
https://www.ncbi.nlm.nih.gov/pubmed/27921270
http://dx.doi.org/10.1186/s13568-016-0297-6