SEOM Clinical Guideline for gastrointestinal sarcomas (GIST) (2016)

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the digestive tract, and this disease has served as a paradigmatic model for successful rational development of targeted therapies. The introduction of tyrosine kinase inhibitors with activity against KIT/PDGFRA in...

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Autores principales: Poveda, A., Martinez, V., Serrano, C., Sevilla, I., Lecumberri, M. J., de Beveridge, R. D., Estival, A., Vicente, D., Rubió, J., Martin-Broto, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Clinical Guides in Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138245/
https://www.ncbi.nlm.nih.gov/pubmed/27896638
http://dx.doi.org/10.1007/s12094-016-1579-9
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author Poveda, A.
Martinez, V.
Serrano, C.
Sevilla, I.
Lecumberri, M. J.
de Beveridge, R. D.
Estival, A.
Vicente, D.
Rubió, J.
Martin-Broto, J.
author_facet Poveda, A.
Martinez, V.
Serrano, C.
Sevilla, I.
Lecumberri, M. J.
de Beveridge, R. D.
Estival, A.
Vicente, D.
Rubió, J.
Martin-Broto, J.
author_sort Poveda, A.
collection PubMed
description Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the digestive tract, and this disease has served as a paradigmatic model for successful rational development of targeted therapies. The introduction of tyrosine kinase inhibitors with activity against KIT/PDGFRA in both localized and advanced stages has remarkably improved the survival in a disease formerly deemed resistant to all systemic therapies. The Spanish Society of Medical Oncology (SEOM) guidelines provide a multidisciplinary and updated consensus for the diagnosis and treatment of GIST patients. We strongly encourage that the managing of these patients should be performed within multidisciplinary teams in reference centers.
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spelling pubmed-51382452016-12-21 SEOM Clinical Guideline for gastrointestinal sarcomas (GIST) (2016) Poveda, A. Martinez, V. Serrano, C. Sevilla, I. Lecumberri, M. J. de Beveridge, R. D. Estival, A. Vicente, D. Rubió, J. Martin-Broto, J. Clin Transl Oncol Clinical Guides in Oncology Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the digestive tract, and this disease has served as a paradigmatic model for successful rational development of targeted therapies. The introduction of tyrosine kinase inhibitors with activity against KIT/PDGFRA in both localized and advanced stages has remarkably improved the survival in a disease formerly deemed resistant to all systemic therapies. The Spanish Society of Medical Oncology (SEOM) guidelines provide a multidisciplinary and updated consensus for the diagnosis and treatment of GIST patients. We strongly encourage that the managing of these patients should be performed within multidisciplinary teams in reference centers. Springer International Publishing 2016-11-28 2016 /pmc/articles/PMC5138245/ /pubmed/27896638 http://dx.doi.org/10.1007/s12094-016-1579-9 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Clinical Guides in Oncology
Poveda, A.
Martinez, V.
Serrano, C.
Sevilla, I.
Lecumberri, M. J.
de Beveridge, R. D.
Estival, A.
Vicente, D.
Rubió, J.
Martin-Broto, J.
SEOM Clinical Guideline for gastrointestinal sarcomas (GIST) (2016)
title SEOM Clinical Guideline for gastrointestinal sarcomas (GIST) (2016)
title_full SEOM Clinical Guideline for gastrointestinal sarcomas (GIST) (2016)
title_fullStr SEOM Clinical Guideline for gastrointestinal sarcomas (GIST) (2016)
title_full_unstemmed SEOM Clinical Guideline for gastrointestinal sarcomas (GIST) (2016)
title_short SEOM Clinical Guideline for gastrointestinal sarcomas (GIST) (2016)
title_sort seom clinical guideline for gastrointestinal sarcomas (gist) (2016)
topic Clinical Guides in Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138245/
https://www.ncbi.nlm.nih.gov/pubmed/27896638
http://dx.doi.org/10.1007/s12094-016-1579-9
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