Cargando…

Mitogen-activated protein kinases (MAPKs) are modulated during Francisella tularensis infection, but inhibition of extracellular-signal-regulated kinases (ERKs) is of limited therapeutic benefit

Francisella tularensis is a Gram-negative intracellular bacterium that causes the disease tularemia. The disease can be fatal if left untreated and there is currently no licenced vaccine available; the identification of new therapeutic targets is therefore required. Toll-like receptors represent an...

Descripción completa

Detalles Bibliográficos
Autores principales: Saint, R. J., D’Elia, R. V., Bryant, C., Clark, G. C., Atkins, H. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138274/
https://www.ncbi.nlm.nih.gov/pubmed/27714591
http://dx.doi.org/10.1007/s10096-016-2754-1