Swift and Complete Healing of Digital Ulcers after Macitentan Treatment

Digital ulcers are a burdensome and painful condition with sparse options of treatment. We report the case of a 78-year-old female patient with limited cutaneous systemic sclerosis that sequentially developed digital ulcers. After the appearance of digital ulcers in the soles of her feet she was suc...

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Detalles Bibliográficos
Autor principal: Giner Serret, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138464/
https://www.ncbi.nlm.nih.gov/pubmed/27994906
http://dx.doi.org/10.1155/2016/1718309
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author Giner Serret, Emilio
author_facet Giner Serret, Emilio
author_sort Giner Serret, Emilio
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description Digital ulcers are a burdensome and painful condition with sparse options of treatment. We report the case of a 78-year-old female patient with limited cutaneous systemic sclerosis that sequentially developed digital ulcers. After the appearance of digital ulcers in the soles of her feet she was successfully treated with bosentan. The report of two new digital ulcers in her hands 9 months later alongside with elevated transaminase levels led to a switch to macitentan treatment. A swift and complete healing of both digital ulcers was observed after 3 months, with the restoration of normal biochemical values.
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spelling pubmed-51384642016-12-19 Swift and Complete Healing of Digital Ulcers after Macitentan Treatment Giner Serret, Emilio Case Rep Rheumatol Case Report Digital ulcers are a burdensome and painful condition with sparse options of treatment. We report the case of a 78-year-old female patient with limited cutaneous systemic sclerosis that sequentially developed digital ulcers. After the appearance of digital ulcers in the soles of her feet she was successfully treated with bosentan. The report of two new digital ulcers in her hands 9 months later alongside with elevated transaminase levels led to a switch to macitentan treatment. A swift and complete healing of both digital ulcers was observed after 3 months, with the restoration of normal biochemical values. Hindawi Publishing Corporation 2016 2016-11-22 /pmc/articles/PMC5138464/ /pubmed/27994906 http://dx.doi.org/10.1155/2016/1718309 Text en Copyright © 2016 Emilio Giner Serret. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Giner Serret, Emilio
Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
title Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
title_full Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
title_fullStr Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
title_full_unstemmed Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
title_short Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
title_sort swift and complete healing of digital ulcers after macitentan treatment
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138464/
https://www.ncbi.nlm.nih.gov/pubmed/27994906
http://dx.doi.org/10.1155/2016/1718309
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