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Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits

Ultrasound microbubble combined optic protection drugs have obvious protective effect on optic nerve damage. This way of targeting drug delivery is becoming more simple, not through the whole body metabolism, avoiding drug via blood circulation when facing the decomposition and the environment in th...

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Detalles Bibliográficos
Autores principales: Shen, Xiaoli, Huang, Lina, Ma, Dahui, Zhao, Jun, Xie, Yi, Li, Qiang, Zeng, Aineng, Zeng, Kun, Tian, Ruyin, Wang, Tianfu, Chen, Siping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138486/
https://www.ncbi.nlm.nih.gov/pubmed/27994883
http://dx.doi.org/10.1155/2016/4235923
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author Shen, Xiaoli
Huang, Lina
Ma, Dahui
Zhao, Jun
Xie, Yi
Li, Qiang
Zeng, Aineng
Zeng, Kun
Tian, Ruyin
Wang, Tianfu
Chen, Siping
author_facet Shen, Xiaoli
Huang, Lina
Ma, Dahui
Zhao, Jun
Xie, Yi
Li, Qiang
Zeng, Aineng
Zeng, Kun
Tian, Ruyin
Wang, Tianfu
Chen, Siping
author_sort Shen, Xiaoli
collection PubMed
description Ultrasound microbubble combined optic protection drugs have obvious protective effect on optic nerve damage. This way of targeting drug delivery is becoming more simple, not through the whole body metabolism, avoiding drug via blood circulation when facing the decomposition and the environment in the interference and destruction process of drugs, to maximize the guarantee to reach target organs of drug concentration and to reache the maximum therapeutic effect. The technique of ultrasound microbubbles is safe, controllable, nonimmunogenic, and repeatable. It provides us with a novel idea in the administration of neuroprotective drugs.
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spelling pubmed-51384862016-12-19 Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits Shen, Xiaoli Huang, Lina Ma, Dahui Zhao, Jun Xie, Yi Li, Qiang Zeng, Aineng Zeng, Kun Tian, Ruyin Wang, Tianfu Chen, Siping J Ophthalmol Research Article Ultrasound microbubble combined optic protection drugs have obvious protective effect on optic nerve damage. This way of targeting drug delivery is becoming more simple, not through the whole body metabolism, avoiding drug via blood circulation when facing the decomposition and the environment in the interference and destruction process of drugs, to maximize the guarantee to reach target organs of drug concentration and to reache the maximum therapeutic effect. The technique of ultrasound microbubbles is safe, controllable, nonimmunogenic, and repeatable. It provides us with a novel idea in the administration of neuroprotective drugs. Hindawi Publishing Corporation 2016 2016-11-22 /pmc/articles/PMC5138486/ /pubmed/27994883 http://dx.doi.org/10.1155/2016/4235923 Text en Copyright © 2016 Xiaoli Shen et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Shen, Xiaoli
Huang, Lina
Ma, Dahui
Zhao, Jun
Xie, Yi
Li, Qiang
Zeng, Aineng
Zeng, Kun
Tian, Ruyin
Wang, Tianfu
Chen, Siping
Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits
title Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits
title_full Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits
title_fullStr Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits
title_full_unstemmed Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits
title_short Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits
title_sort ultrasound microbubbles enhance the neuroprotective effect of mouse nerve growth factor on intraocular hypertension-induced neuroretina damage in rabbits
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138486/
https://www.ncbi.nlm.nih.gov/pubmed/27994883
http://dx.doi.org/10.1155/2016/4235923
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