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Mitragyna speciosa Leaf Extract Exhibits Antipsychotic-Like Effect with the Potential to Alleviate Positive and Negative Symptoms of Psychosis in Mice

In this study, we investigated the antipsychotic-like effect of methanolic extract of Mitragyna speciosa leaf (MMS) using in vivo and ex vivo studies. In vivo studies comprised of apomorphine-induced climbing behavior, haloperidol-induced catalepsy, and ketamine-induced social withdrawal tests in mi...

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Detalles Bibliográficos
Autores principales: Vijeepallam, Kamini, Pandy, Vijayapandi, Kunasegaran, Thubasni, Murugan, Dharmani D., Naidu, Murali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138496/
https://www.ncbi.nlm.nih.gov/pubmed/27999544
http://dx.doi.org/10.3389/fphar.2016.00464