Cargando…

Mitragyna speciosa Leaf Extract Exhibits Antipsychotic-Like Effect with the Potential to Alleviate Positive and Negative Symptoms of Psychosis in Mice

In this study, we investigated the antipsychotic-like effect of methanolic extract of Mitragyna speciosa leaf (MMS) using in vivo and ex vivo studies. In vivo studies comprised of apomorphine-induced climbing behavior, haloperidol-induced catalepsy, and ketamine-induced social withdrawal tests in mi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vijeepallam, Kamini, Pandy, Vijayapandi, Kunasegaran, Thubasni, Murugan, Dharmani D., Naidu, Murali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138496/ https://www.ncbi.nlm.nih.gov/pubmed/27999544 http://dx.doi.org/10.3389/fphar.2016.00464

Ejemplares similares

Effect of Noni (Morinda citrifolia Linn.) Fruit and Its Bioactive Principles Scopoletin and Rutin on Rat Vas Deferens Contractility: An Ex Vivo Study
por: Pandy, Vijayapandi, et al.
Publicado: (2014)

Antipsychotic-like activity of scopoletin and rutin against the positive symptoms of schizophrenia in mouse models
por: Pandy, Vijayapandi, et al.
Publicado: (2017)

The ethyl acetate fraction of a methanolic extract of unripe noni (Morinda citrifolia Linn.) fruit exhibits a biphasic effect on the dopaminergic system in mice
por: Pandy, Vijayapandi, et al.
Publicado: (2017)

The Adverse Cardiovascular Effects and Cardiotoxicity of Kratom (Mitragyna speciosa Korth.): A Comprehensive Review
por: Leong Bin Abdullah, Mohammad Farris Iman, et al.
Publicado: (2021)

Kratom (Mitragyna speciosa)-Induced Hepatitis
por: Allison, Devin R., et al.
Publicado: (2022)

Subchronic toxicity study of standardized methanolic extract of Mitragyna speciosa Korth in Sprague-Dawley Rats
por: Ilmie, Mohd U., et al.
Publicado: (2015)

PHYTOCHEMICAL, PHARMACOLOGICAL AND BIOLOGICAL PROFILES OF TRAGIA SPECIES (FAMILY: EUPHORBIACEAE)
por: Reddy, Bonam Srinivasa, et al.
Publicado: (2017)

Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS
por: Veeramohan, Rubashiny, et al.
Publicado: (2018)

Leaf Anatomy and Micromorphology Characteristics of Ketum [Mitragyna speciosa (Korth.) Havil.] (Rubiaceae)
por: Ghazalli, Mohd Norfaizal, et al.
Publicado: (2021)

Assessment of Cardiovascular Functioning Among Regular Kratom (Mitragyna speciosa Korth) Users: A Case Series
por: Leong Bin Abdullah, Mohammad Farris Iman, et al.
Publicado: (2021)

Can Kratom (Mitragyna speciosa) Alleviate COVID-19 Pain? A Case Study
por: Metastasio, Antonio, et al.
Publicado: (2020)

A Case of Hyperkalemia Induced by Kratom (Mitragyna speciosa)
por: Torres-Ortiz, Aldo, et al.
Publicado: (2022)

Association between kratom (Mitragyna speciosa) use and metabolic syndrome
por: La-up, Aroon, et al.
Publicado: (2022)

Effects of Nutrient Fertility on Growth and Alkaloidal Content in Mitragyna speciosa (Kratom)
por: Zhang, Mengzi, et al.
Publicado: (2020)

First Report of Meloidogyne Incognita Infecting Mitragyna Speciosa in the United States
por: Habteweld, Alemayehu, et al.
Publicado: (2022)

Clinical Implications of Kratom (Mitragyna speciosa) Use: a Literature Review
por: Prevete, Elisabeth, et al.
Publicado: (2023)

Kratom (Mitragyna speciosa) and COVID-19: How about the current evidence?
por: Kleebayoon, Amnuay, et al.
Publicado: (2023)

Methanolic Extract of Morinda citrifolia L. (Noni) Unripe Fruit Attenuates Ethanol-Induced Conditioned Place Preferences in Mice
por: Khan, Yasmin, et al.
Publicado: (2016)

Mitragyna speciosa: Clinical, Toxicological Aspects and Analysis in Biological and Non-Biological Samples
por: Meireles, Vânia, et al.
Publicado: (2019)

Lipid profile of regular kratom (Mitragyna speciosa Korth.) users in the community setting
por: Leong Bin Abdullah, Mohammad Farris Iman, et al.
Publicado: (2020)

Variations in mitragynine content in the naturally growing Kratom (Mitragyna speciosa) population of Thailand
por: Leksungnoen, Nisa, et al.
Publicado: (2022)

Investigating the Impact of Kratom (Mitragyna speciosa) Use Upon Male Sexual Health
por: Deebel, Nicholas A, et al.
Publicado: (2023)

Biphasic Effects of α-Asarone on Immobility in the Tail Suspension Test: Evidence for the Involvement of the Noradrenergic and Serotonergic Systems in Its Antidepressant-Like Activity
por: Chellian, Ranjithkumar, et al.
Publicado: (2016)

Antipsychotic-like activity of Noni (Morinda citrifolia Linn.) in mice
por: Pandy, Vijayapandi, et al.
Publicado: (2012)

Acute, Sublethal, and Developmental Toxicity of Kratom (Mitragyna speciosa Korth.) Leaf Preparations on Caenorhabditis elegans as an Invertebrate Model for Human Exposure
por: Hughes, Samantha, et al.
Publicado: (2022)

Understanding the Physicochemical Properties of Mitragynine, a Principal Alkaloid of Mitragyna speciosa, for Preclinical Evaluation
por: Ramanathan, Surash, et al.
Publicado: (2015)

Assessing the quality of information provided on websites selling Kratom (Mitragyna speciosa) to consumers in Canada
por: Ng, Jeremy Y., et al.
Publicado: (2021)

Health Effects Associated With Kratom (Mitragyna speciosa) and Polysubstance Use: A Narrative Review
por: Striley, Catherine W, et al.
Publicado: (2022)

Assessment of the possible health risks associated with the consumption of botanical preparations of Mitragyna speciosa (kratom)
por: Papadi, Georgia, et al.
Publicado: (2022)

Evaluation of the Effects of Mitragyna speciosa Alkaloid Extract on Cytochrome P450 Enzymes Using a High Throughput Assay
por: Kong, Wai Mun, et al.
Publicado: (2011)

Differentiation of Mitragyna speciosa, a narcotic plant, from allied Mitragyna species using DNA barcoding-high-resolution melting (Bar-HRM) analysis
por: Tungphatthong, Chayapol, et al.
Publicado: (2021)

Antinociceptive Action of Isolated Mitragynine from Mitragyna Speciosa through Activation of Opioid Receptor System
por: Shamima, Abdul Rahman, et al.
Publicado: (2012)

Current and Future Potential Impact of COVID-19 on Kratom (Mitragyna speciosa Korth.) Supply and Use
por: Singh, Darshan, et al.
Publicado: (2020)

Plant growth and phytoactive alkaloid synthesis in kratom [Mitragyna speciosa (Korth.)] in response to varying radiance
por: Zhang, Mengzi, et al.
Publicado: (2022)

Inhibition of α-Glucosidase and Pancreatic Lipase Properties of Mitragyna speciosa (Korth.) Havil. (Kratom) Leaves
por: Limcharoen, Thanchanok, et al.
Publicado: (2022)

Seasonal and Geographic Variation in Alkaloid Content of Kratom (Mitragyna speciosa (Korth.) Havil.) from Thailand
por: Sengnon, Narumon, et al.
Publicado: (2023)

In Vitro and in Vivo Effects of Three Different Mitragyna speciosa Korth Leaf Extracts on Phase II Drug Metabolizing Enzymes—Glutathione Transferases (GSTs)
por: Azizi, Juzaili, et al.
Publicado: (2010)

The evaluation of antinociceptive activity of alkaloid, methanolic, and aqueous extracts of Malaysian Mitragyna speciosa Korth leaves in rats
por: Sabetghadam, Azadeh, et al.
Publicado: (2010)

Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions
por: Todd, D. A., et al.
Publicado: (2020)

The Mitragyna speciosa (Kratom) Genome: a resource for data-mining potent pharmaceuticals that impact human health
por: Brose, Julia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_r8a6fh62ipv5b5k4eghgqsvij9