Protein inhibitor of activated STAT 4 (PIAS4) regulates liver fibrosis through modulating SMAD3 activity

Excessive fibrogenesis disrupts normal liver structure, impairs liver function, and precipitates the development of cirrhosis, an irreversible end-stage liver disease. A host of factors including nutrition surplus contribute to liver fibrosis but the underlying mechanism is not fully understood. In...

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Detalles Bibliográficos
Autores principales: Xu, Huihui, Fan, Zhiwen, Tian, Wenfang, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138582/
https://www.ncbi.nlm.nih.gov/pubmed/27924068
http://dx.doi.org/10.7555/JBR.30.20160049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138582/
https://www.ncbi.nlm.nih.gov/pubmed/27924068
http://dx.doi.org/10.7555/JBR.30.20160049

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