Proteomic profiling reveals that collismycin A is an iron chelator

Collismycin A (CMA), a microbial product, has anti-proliferative activity against cancer cells, but the mechanism of its action remains unknown. Here, we report the identification of the molecular target of CMA by ChemProteoBase, a proteome-based approach for drug target identification. ChemProteoBa...

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Detalles Bibliográficos
Autores principales: Kawatani, Makoto, Muroi, Makoto, Wada, Akira, Inoue, Gyo, Futamura, Yushi, Aono, Harumi, Shimizu, Kenshirou, Shimizu, Takeshi, Igarashi, Yasuhiro, Takahashi-Ando, Naoko, Osada, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138588/
https://www.ncbi.nlm.nih.gov/pubmed/27922079
http://dx.doi.org/10.1038/srep38385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138588/
https://www.ncbi.nlm.nih.gov/pubmed/27922079
http://dx.doi.org/10.1038/srep38385

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