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Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains
The Cag Type IV secretion system, which contributes to inflammation and cancerogenesis during chronic infection, is one of the major virulence factors of the bacterial gastric pathogen Helicobacter pylori. We have generated and characterized a series of non-marked site-directed chromosomal mutants i...
Autores principales: | Bönig, Tobias, Olbermann, Patrick, Bats, Simon H., Fischer, Wolfgang, Josenhans, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138618/ https://www.ncbi.nlm.nih.gov/pubmed/27922023 http://dx.doi.org/10.1038/srep38101 |
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