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Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains

The Cag Type IV secretion system, which contributes to inflammation and cancerogenesis during chronic infection, is one of the major virulence factors of the bacterial gastric pathogen Helicobacter pylori. We have generated and characterized a series of non-marked site-directed chromosomal mutants i...

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Detalles Bibliográficos
Autores principales: Bönig, Tobias, Olbermann, Patrick, Bats, Simon H., Fischer, Wolfgang, Josenhans, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138618/
https://www.ncbi.nlm.nih.gov/pubmed/27922023
http://dx.doi.org/10.1038/srep38101

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