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Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention

Non-alcoholic steatohepatitis (NASH) is characterized by liver lipid accumulation and inflammation. The mechanisms that trigger hepatic inflammation are poorly understood and subsequently, no specific non-invasive markers exist. We previously demonstrated a reduction in the plasma lysosomal enzyme,...

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Detalles Bibliográficos
Autores principales: Walenbergh, Sofie M. A., Houben, Tom, Rensen, Sander S., Bieghs, Veerle, Hendrikx, Tim, van Gorp, Patrick J., Oligschlaeger, Yvonne, Jeurissen, Mike L. J., Gijbels, Marion J. J., Buurman, Wim A., Vreugdenhil, Anita C. E., Greve, Jan Willem M., Plat, Jogchum, Hofker, Marten H., Kalhan, Satish, Pihlajamäki, Jussi, Lindsey, Patrick, Koek, Ger H., Shiri-Sverdlov, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138820/
https://www.ncbi.nlm.nih.gov/pubmed/27922112
http://dx.doi.org/10.1038/srep38278

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