Design and mechanistic insight into ultrafast calcium indicators for monitoring intracellular calcium dynamics

Calmodulin-based genetically encoded fluorescent calcium indicators (GCaMP-s) are powerful tools of imaging calcium dynamics from cells to freely moving animals. High affinity indicators with slow kinetics however distort the temporal profile of calcium transients. Here we report the development of...

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Detalles Bibliográficos
Autores principales: Helassa, Nordine, Podor, Borbala, Fine, Alan, Török, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138832/
https://www.ncbi.nlm.nih.gov/pubmed/27922063
http://dx.doi.org/10.1038/srep38276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138832/
https://www.ncbi.nlm.nih.gov/pubmed/27922063
http://dx.doi.org/10.1038/srep38276

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