Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I

Crude Amaryllidaceae alkaloids (AAs) extracted from Lycoris radiata are reported to exhibit significant anti-cancer activity. However, the specific alkaloids responsible for the pharmacodynamic activity and their targets still remain elusive. In this context, we strived to combine affinity ultrafilt...

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Detalles Bibliográficos
Autores principales: Chen, Gui-Lin, Tian, Yong-Qiang, Wu, Jian-Lin, Li, Na, Guo, Ming-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138836/
https://www.ncbi.nlm.nih.gov/pubmed/27922057
http://dx.doi.org/10.1038/srep38284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138836/
https://www.ncbi.nlm.nih.gov/pubmed/27922057
http://dx.doi.org/10.1038/srep38284

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