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Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I
Crude Amaryllidaceae alkaloids (AAs) extracted from Lycoris radiata are reported to exhibit significant anti-cancer activity. However, the specific alkaloids responsible for the pharmacodynamic activity and their targets still remain elusive. In this context, we strived to combine affinity ultrafilt...
Autores principales: | Chen, Gui-Lin, Tian, Yong-Qiang, Wu, Jian-Lin, Li, Na, Guo, Ming-Quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138836/ https://www.ncbi.nlm.nih.gov/pubmed/27922057 http://dx.doi.org/10.1038/srep38284 |
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