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Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle
Lipid droplets (LD) play a central role in lipid homeostasis by controlling transient fatty acid (FA) storage and release from triacylglycerols stores, while preventing high levels of cellular toxic lipids. This crucial function in oxidative tissues is altered in obesity and type 2 diabetes. Perilip...
Autores principales: | Laurens, Claire, Bourlier, Virginie, Mairal, Aline, Louche, Katie, Badin, Pierre-Marie, Mouisel, Etienne, Montagner, Alexandra, Marette, André, Tremblay, Angelo, Weisnagel, John S., Guillou, Hervé, Langin, Dominique, Joanisse, Denis R., Moro, Cedric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138838/ https://www.ncbi.nlm.nih.gov/pubmed/27922115 http://dx.doi.org/10.1038/srep38310 |
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