Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis

BACKGROUND: Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperproliferation and altered keratinocyte differentiation and inflammation and is caused by the interplay of genetic and environmental factors. Previous studies have revealed that DNA methylation (DNAm) and gen...

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Detalles Bibliográficos
Autores principales: Zhou, Fusheng, Shen, Changbing, Xu, Jingkai, Gao, Jing, Zheng, Xiaodong, Ko, Randy, Dou, Jinfa, Cheng, Yuyan, Zhu, Caihong, Xu, Shuangjun, Tang, Xianfa, Zuo, Xianbo, Yin, Xianyong, Cui, Yong, Sun, Liangdan, Tsoi, Lam C., Hsu, Yi-Hsiang, Yang, Sen, Zhang, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139011/
https://www.ncbi.nlm.nih.gov/pubmed/27980695
http://dx.doi.org/10.1186/s13148-016-0297-z

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