Preparation and structural determination of four metabolites of senkyunolide I in rats using ultra performance liquid chromatography/quadrupole-time-of-flight tandem mass and nuclear magnetic resonance spectra

BACKGROUND: Senkyunolide I (SEI) is one of the most important bioactive phthalides of Ligusticum chuanxiong Hort. (Umbelliferae), a Traditional Chinese Medicine. Our previous studies suggested that it might be developed as a potential treatment for migraine. METHODS: In this paper, we aimed to isola...

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Detalles Bibliográficos
Autores principales: Ma, Qiang, Ma, Cong, Wu, Fei, Xiong, Yao-kun, Feng, Yi, Liang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139061/
https://www.ncbi.nlm.nih.gov/pubmed/27919258
http://dx.doi.org/10.1186/s12906-016-1472-7

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