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Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers

BACKGROUND: Measures of spatial intratumor heterogeneity are potentially important diagnostic biomarkers for cancer progression, proliferation, and response to therapy. Spatial relationships among cells including cancer and stromal cells in the tumor microenvironment (TME) are key contributors to he...

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Detalles Bibliográficos
Autores principales:	Spagnolo, Daniel M., Gyanchandani, Rekha, Al-Kofahi, Yousef, Stern, Andrew M., Lezon, Timothy R., Gough, Albert, Meyer, Dan E., Ginty, Fiona, Sarachan, Brion, Fine, Jeffrey, Lee, Adrian V., Taylor, D. Lansing, Chennubhotla, S. Chakra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139455/ https://www.ncbi.nlm.nih.gov/pubmed/27994939 http://dx.doi.org/10.4103/2153-3539.194839

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