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History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines

Influenza is a highly infectious airborne disease with an important epidemiological and societal burden; annual epidemics and pandemics have occurred since ancient times, causing tens of millions of deaths. A hundred years after this virus was first isolated, influenza vaccines are an important infl...

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Autores principales: BARBERIS, I., MYLES, P., AULT, S.K., BRAGAZZI, N.L., MARTINI, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore SRL 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139605/
https://www.ncbi.nlm.nih.gov/pubmed/27980374
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author BARBERIS, I.
MYLES, P.
AULT, S.K.
BRAGAZZI, N.L.
MARTINI, M.
author_facet BARBERIS, I.
MYLES, P.
AULT, S.K.
BRAGAZZI, N.L.
MARTINI, M.
author_sort BARBERIS, I.
collection PubMed
description Influenza is a highly infectious airborne disease with an important epidemiological and societal burden; annual epidemics and pandemics have occurred since ancient times, causing tens of millions of deaths. A hundred years after this virus was first isolated, influenza vaccines are an important influenza prevention strategy and the preparations used display good safety and tolerability profiles. Innovative tools, such as recombinant technologies and intra-dermal devices, are currently being investigated in order to improve the immunological response. The recurring mutations of influenza strains has prompted the recent introduction of a quadrivalent inactivated vaccine. In the near future, scientific research will strive to produce a long-lasting universal vaccine containing an antigen that will offer protection against all influenza virus strains.
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spelling pubmed-51396052016-12-15 History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines BARBERIS, I. MYLES, P. AULT, S.K. BRAGAZZI, N.L. MARTINI, M. J Prev Med Hyg Overview Influenza is a highly infectious airborne disease with an important epidemiological and societal burden; annual epidemics and pandemics have occurred since ancient times, causing tens of millions of deaths. A hundred years after this virus was first isolated, influenza vaccines are an important influenza prevention strategy and the preparations used display good safety and tolerability profiles. Innovative tools, such as recombinant technologies and intra-dermal devices, are currently being investigated in order to improve the immunological response. The recurring mutations of influenza strains has prompted the recent introduction of a quadrivalent inactivated vaccine. In the near future, scientific research will strive to produce a long-lasting universal vaccine containing an antigen that will offer protection against all influenza virus strains. Pacini Editore SRL 2016-09 /pmc/articles/PMC5139605/ /pubmed/27980374 Text en © Copyright by Pacini Editore SRL, Pisa, Italy http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License, which permits for noncommercial use, distribution, and reproduction in any digital medium, provided the original work is properly cited and is not altered in any way. For details, please refer to http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Overview
BARBERIS, I.
MYLES, P.
AULT, S.K.
BRAGAZZI, N.L.
MARTINI, M.
History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines
title History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines
title_full History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines
title_fullStr History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines
title_full_unstemmed History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines
title_short History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines
title_sort history and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines
topic Overview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139605/
https://www.ncbi.nlm.nih.gov/pubmed/27980374
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